266 Rising use of adjuvant radiation treatment in melanoma
نویسندگان
چکیده
منابع مشابه
Adjuvant Treatment of Melanoma
Melanomas represent 4% of all malignant tumors of the skin, yet account for 80% of deaths from skin cancer.While in the early stages patients can be successfully treated with surgical resection, metastatic melanoma prognosis is dismal. Several oncogenes have been identified in melanoma as BRAF, NRAS, c-Kit, and GNA11 GNAQ, each capable of activating MAPK pathway that increases cell proliferatio...
متن کاملAdjuvant Melanoma Treatment Strategies
Reduced function mutations in the insulin/IGF-I signaling pathway increase maximal lifespan and health span in many species. Calorie restriction (CR) decreases serum IGF-1 concentration by ~40%, protects against cancer and slows aging in rodents. However, the long-term effects of CR with adequate nutrition on circulating IGF-1 levels in humans are unknown. Here we report data from two long-term...
متن کاملAdjuvant radiation therapy in metastatic lymph nodes from melanoma
PURPOSE To analyze the outcome after adjuvant radiation therapy with standard fractionation regimen in metastatic lymph nodes (LN) from cutaneous melanoma. PATIENTS AND METHODS 86 successive patients (57 men) were treated for locally advanced melanoma in our institution. 60 patients (69%) underwent LN dissection followed by radiation therapy (RT), while 26 patients (31%) had no radiotherapy. ...
متن کاملAdjuvant Radiation for Malignant Melanoma: The KUMC Experience
Background. The role of external beam radiation in the treatment of melanoma remains controversial. While melanoma is no longer considered radio-resistant, the indications and outcomes for adjuvant radiation therapy in melanoma patients are still evolving. Methods. A retrospective review was conducted of patients diagnosed with malignant melanoma and treated with postoperative radiation therapy...
متن کاملRadiation therapy as primary and adjuvant treatment for local and regional melanoma.
BACKGROUND The role of radiation therapy as primary and adjuvant therapy for localized or locally advanced melanoma is controversial. METHODS To develop evidence-based guidelines, PubMed was searched using the keywords melanoma AND (radiation OR radiotherapy). These references were reviewed and the relevant articles selected. The articles were then reviewed for further references. Because of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.342